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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3S0737 | Flavokawain A | Flavokavain A | Apoptosis , p38 MAPK |
NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant... | |||
T5715 | (E)-Flavokawain A | FLAVOKAVAIN A(P) | Apoptosis , P450 |
(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. | |||
T5753 | Flavokawain C | Apoptosis | |
Flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava.FKC has the potential to be developed into chemotherapeutic drug for the treatment of colon adenocarcinoma. | |||
T83890 | Flavokawain 1i | Flavokavain 1i | |
Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties. At a concentration of 30 µM, it suppresses the growth of gefitinib-resistant H1975 ... | |||
TN1645 | Flavokawain C | NADPH-oxidase , MAPK , AChR | |
Flavokawain C is a melanogenesis inhibitor, it inhibited melanogenesis with IC50 values of 6.9 μM. Flavokawain C has anti-tumor activity, it inhibited cell cycle and promoted apoptosis, associated with endoplasmic reticu... |